Search for tag: "basic science"

Smartphone imaging of the mouse fundus

Michael Peng talks about using smartphone cameras to take images of the mouse fundus.

From  Michael Hawkes 0 plays 0  

Glaucoma associated Optineurin mutation causes mitophagy defects

Kavitha Anbarasu talks about a glaucoma-associated Optineurin<sup>E50K</sup> mutation causing mitophagy defects, leading to human retinal ganglion cell death.

From  Michael Hawkes 8 plays 0  

Targeting Thioredoxin-Interacting Protein (TXNIP) in the trabecular meshwork

Chevy Singh discusses targeting Thioredoxin-Interacting Protein (TXNIP) in the trabecular meshwork to prevent high glucose-mediated ocular hypertension.

From  Michael Hawkes 1 plays 0  

From the Bench to Bedside: Rho Kinase (ROCK) Inhibitors as a Therapy for Glaucoma

Drs. Elizabeth Martin and Padhu Pattabiraman present the Science of Disease Grand Rounds in September. During their presentation they discuss glaucoma and Rho kinase inhibitors in the clinic and in…

From  Michael Hawkes 3 plays 0  

The canonical Wnt signaling pathway inhibits glucocorticoid receptor signaling pathway in the trabecular meshwork

Chenna Sugali talks about how the canonical Wnt signaling pathway inhibits glucocorticoid receptor signaling pathway in the trabecular meshwork.

From  Michael Hawkes 3 plays 0  

Systems biology approach to monitor protein renewal in terminally differentiated retinal neurons

Mohammad Harun-Or-Rashid talks about a systems biology approach to monitor protein renewal in terminally differentiated retinal neurons

From  Michael Hawkes 1 plays 0  

Neurodegeneration of glaucoma patient retinal ganglion cells derived from human pluripotent stem cells

K.C. Huang talks about neurodegeneration of glaucoma patient retinal ganglion cells derived from human pluripotent stem cells.

From  Michael Hawkes 3 plays 0  

Cannabinoid regulation of tearing

Jenna Billingsley talks about cannabinoid regulation of tearing

From  Michael Hawkes 1 plays 0  

Circadian rhythm disruption results in visual dysfunction

Deepa Mathew discusses how disruption of the circadian rhythm results in visual dysfunction.

From  Michael Hawkes 7 plays 0  

The tree shrew: A novel model for ophthalmic diseases

Brian Samuels delivers a presentation on the tree shrew as a novel model for ophthalmic diseases.

From  Michael Hawkes 6 plays 0  

AAV8 mediated expression of shRNA targeting soluble epoxide hydrolase suppresses choroidal neovascularization

Bomina Park talks about AAV8 mediated expression of shRNA targeting soluble epoxide hydrolase suppresses choroidal neovascularization

From  Michael Hawkes 14 plays 0  

Selection free method to enhance gene transfer efficiency in human stem cells for CRISPR/Cas9 based disease modeling

Michelle Surma discusses selection free method to enhance gene transfer efficiency in human stem cells for CRISPR/Cas9 based disease modeling

From  Michael Hawkes 0 plays 0  

Clusterin regulates lipid biogenesis in the trabecular meshwork

Ting Wang discusses how clusterin regulates lipid biogenesis in the trabecular meshwork.

From  Michael Hawkes 4 plays 0  

The Role of Actin associate proteins in Cross-Linked Actin Networks (CLANs) formation in human trabecular meshwork cells

Jiannong Dai talks about the role of actin associate proteins in Cross-Linked Actin Networks (CLANs) formation in human trabecular meshwork cells.

From  Michael Hawkes 1 plays 0  

Cathepsin K is a critical regulator of collagen 1A and intraocular pressure.

Supriya Vuda discusses Cathepsin K and its role in the regulation of collagen 1A and intraocular pressure.

From  Michael Hawkes 6 plays 0  

Lentiviral gene transfer of human mutant TGFβ2 for a mouse ocular hypertension model: A premilinary study

Michael Peng talks about a lentiviral approach to gene transfer of TGFβ2 for a mouse ocular hypertension model.

From  Michael Hawkes 1 plays 0  

Dexamethasone and Transforming Growth Factor β2 (TGFβ2) inhibits notch signaling pathway in trabecular meshwork

Sachin Ghag discusses how dexamethasone and TGFβ2 inhibits notch signaling pathway in the trabecular meshwork.

From  Michael Hawkes 4 plays 0  

The canonical Wnt signaling pathway inhibits glucocorticoid receptor signaling pathway in the trabecular meshwork

Dr Chenna Sugali discusses the how the canonical Wnt signaling pathway inhibits glucocorticoid signaling pathway in the trabecular meshwork.

From  Michael Hawkes 0 plays 0  

Selection free method to enhance gene transfer efficiency in human stem cells for CRISPR/Cas9 based disease modeling

Michelle Surma discusses a selection free method to enhance gene transfer efficiency in human stem cells for CRISPR/Cas9 based disease modeling

From  Michael Hawkes 1 plays 0  

Soluble epoxide hydrolase as a therpeutic target for choroidal neovascularization

Doctoral candidate Bomina Park talks about the potential of Soluble epoxide hydrolase as a therapeutic target for choroidal neovascularization.

From  Michael Hawkes 9 plays 0  

Regulation of clusterin, a secretory chaperone protein, in trabecular meshwork

Dr Avinash Soundararajan give a talk on the regulation of clusterin in the trabecular meshwork.

From  Michael Hawkes 4 plays 0