Search for tag: "basic science"
Ophthalmology Grand Rounds September 2024 - Science of DiseaseIn this Science of Disease talk, Massood Mohammadi, MD presents a quick look at glaucoma pathophysiology and treatment while Arupratan Das, PhD follows with a presentation on the restoration of…
From Michael Hawkes
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Smartphone imaging of the mouse fundusMichael Peng talks about using smartphone cameras to take images of the mouse fundus.
From Michael Hawkes
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Glaucoma associated Optineurin mutation causes mitophagy defectsKavitha Anbarasu talks about a glaucoma-associated Optineurin<sup>E50K</sup> mutation causing mitophagy defects, leading to human retinal ganglion cell death.
From Michael Hawkes
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Targeting Thioredoxin-Interacting Protein (TXNIP) in the trabecular meshworkChevy Singh discusses targeting Thioredoxin-Interacting Protein (TXNIP) in the trabecular meshwork to prevent high glucose-mediated ocular hypertension.
From Michael Hawkes
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From the Bench to Bedside: Rho Kinase (ROCK) Inhibitors as a Therapy for GlaucomaDrs. Elizabeth Martin and Padhu Pattabiraman present the Science of Disease Grand Rounds in September. During their presentation they discuss glaucoma and Rho kinase inhibitors in the clinic and in…
From Michael Hawkes
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The canonical Wnt signaling pathway inhibits glucocorticoid receptor signaling pathway in the trabecular meshworkChenna Sugali talks about how the canonical Wnt signaling pathway inhibits glucocorticoid receptor signaling pathway in the trabecular meshwork.
From Michael Hawkes
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Systems biology approach to monitor protein renewal in terminally differentiated retinal neuronsMohammad Harun-Or-Rashid talks about a systems biology approach to monitor protein renewal in terminally differentiated retinal neurons
From Michael Hawkes
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Neurodegeneration of glaucoma patient retinal ganglion cells derived from human pluripotent stem cellsK.C. Huang talks about neurodegeneration of glaucoma patient retinal ganglion cells derived from human pluripotent stem cells.
From Michael Hawkes
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Circadian rhythm disruption results in visual dysfunctionDeepa Mathew discusses how disruption of the circadian rhythm results in visual dysfunction.
From Michael Hawkes
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The tree shrew: A novel model for ophthalmic diseasesBrian Samuels delivers a presentation on the tree shrew as a novel model for ophthalmic diseases.
From Michael Hawkes
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AAV8 mediated expression of shRNA targeting soluble epoxide hydrolase suppresses choroidal neovascularizationBomina Park talks about AAV8 mediated expression of shRNA targeting soluble epoxide hydrolase suppresses choroidal neovascularization
From Michael Hawkes
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Selection free method to enhance gene transfer efficiency in human stem cells for CRISPR/Cas9 based disease modelingMichelle Surma discusses selection free method to enhance gene transfer efficiency in human stem cells for CRISPR/Cas9 based disease modeling
From Michael Hawkes
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Clusterin regulates lipid biogenesis in the trabecular meshworkTing Wang discusses how clusterin regulates lipid biogenesis in the trabecular meshwork.
From Michael Hawkes
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The Role of Actin associate proteins in Cross-Linked Actin Networks (CLANs) formation in human trabecular meshwork cellsJiannong Dai talks about the role of actin associate proteins in Cross-Linked Actin Networks (CLANs) formation in human trabecular meshwork cells.
From Michael Hawkes
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Cathepsin K is a critical regulator of collagen 1A and intraocular pressure.Supriya Vuda discusses Cathepsin K and its role in the regulation of collagen 1A and intraocular pressure.
From Michael Hawkes
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Lentiviral gene transfer of human mutant TGFβ2 for a mouse ocular hypertension model: A premilinary studyMichael Peng talks about a lentiviral approach to gene transfer of TGFβ2 for a mouse ocular hypertension model.
From Michael Hawkes
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Dexamethasone and Transforming Growth Factor β2 (TGFβ2) inhibits notch signaling pathway in trabecular meshworkSachin Ghag discusses how dexamethasone and TGFβ2 inhibits notch signaling pathway in the trabecular meshwork.
From Michael Hawkes
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The canonical Wnt signaling pathway inhibits glucocorticoid receptor signaling pathway in the trabecular meshworkDr Chenna Sugali discusses the how the canonical Wnt signaling pathway inhibits glucocorticoid signaling pathway in the trabecular meshwork.
From Michael Hawkes
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Selection free method to enhance gene transfer efficiency in human stem cells for CRISPR/Cas9 based disease modelingMichelle Surma discusses a selection free method to enhance gene transfer efficiency in human stem cells for CRISPR/Cas9 based disease modeling
From Michael Hawkes
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Soluble epoxide hydrolase as a therpeutic target for choroidal neovascularizationDoctoral candidate Bomina Park talks about the potential of Soluble epoxide hydrolase as a therapeutic target for choroidal neovascularization.
From Michael Hawkes
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Regulation of clusterin, a secretory chaperone protein, in trabecular meshworkDr Avinash Soundararajan give a talk on the regulation of clusterin in the trabecular meshwork.
From Michael Hawkes
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